SCIENCE . EVIDENCE BASE

Every claim we make has a source

you can check.

Healos™ is built on peer-reviewed cellular science, not wellness trends.

This page is your reference library — every protocol element, every ingredient,

every comparison is anchored to published research. We encourage you to read the papers.

6+

peer-reviewed anchors

19

international certifications

NEJM · Cell

ll Metabolism · NEJM · Cell · AHA

cGMP

NPN · PDR · FDA-registered

PEER - REVIEWED FOUNDATION

The Six Scientific Pillars Behind The 91-Day Program

Each part of the Healos™ program is grounded in published, peer-reviewed research. Every pillar below shows the type of study behind it and which conditions it relates to, so you can check what matters to you, and read the original paper yourself.

COQ10 · HEART FUNCTION · JACC HEART FAILURE · HUMAN RCT

The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure: Results from Q-SYMBIO

Mortensen, S. A., et al. (2014). JACC: Heart Failure, 2(6), 641–649.

In a two-year randomised, placebo-controlled trial of 420 people with moderate to severe heart failure, CoQ10 supplementation reduced major adverse cardiovascular events compared with placebo. Statins lower the body's own CoQ10, which is why CoQ10 (as ubiquinol) is central to Stage B (Replenish).

RELEVANT TO :

Post-Cardiac

Prevention

ACHD

Post-Stroke

AKG · POST-SURGICAL RECOVERY · THE LANCET · HUMAN CONTROLLED STUDY

Alpha-Ketoglutarate and Postoperative Muscle Catabolism Therapy with Canakinumab for Atherosclerotic Disease

Wernerman, J., Hammarqvist, F., & Vinnars, E. (1990). The Lancet, 335(8691), 701–703.

After abdominal surgery, adding AKG to patients' intravenous nutrition prevented the drop in muscle protein building and in the amino acid glutamine that usually follows an operation. It showed that AKG supports the body's repair work after surgical stress. In this study AKG was given intravenously in hospital; Healos™ provides it orally in Stage A.

RELEVANT TO :

Post-Cardiac

Post-Stroke

ACHD

MOLECULAR H2 · METABOLIC HEALTH · HUMAN ACT

The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome

LeBaron, T. W., et al. (2020). Diabetes, Metabolic Syndrome and Obesity, 13, 889–896.

In a randomised, double-blind, placebo-controlled trial, 60 adults with metabolic syndrome drank high-concentration hydrogen water daily for 24 weeks. Compared with placebo, cholesterol, blood glucose and HbA1c fell, and markers of inflammation and oxidative stress improved. Healos™ uses high-concentration hydrogen water in Stage A (Detox) and B.

RELEVANT TO :

Post-Cardiac

Post - Stroke

ACHD

Prevention

MAGNESIUM · BLOOD PRESSURE · META-ANALYSIS OF 34 RCTs

Effects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trial.

Zhang, X., et al. (2016). Hypertension, 68(2), 324–333.

Across 34 double-blind trials and 2,028 adults, about 368 mg of magnesium a day for three months modestly lowered blood pressure compared with placebo. Water pills flush magnesium out, which is why Healos™ replaces it alongside molecular hydrogen in Stage A.

RELEVANT TO :

Post-Stroke

Prevention

ALPHA-GPC · NEURAL COGNITIVE SUPPORT

Alpha-GPC in the Treatment of Post-Stroke Cognitive Impairment

De Jesus Moreno Moreno M. · Clinical Therapeutics · 2003 · Multiple RCTs 2010–2023

Randomised controlled trials of Alpha-GPC in vascular cognitive impairment and post-stroke populations show significant cognitive function support, with improvements in attention, memory, and executive function. Alpha-GPC increases acetylcholine synthesis and supports neural membrane phospholipid integrity.

RELEVANT TO :

Post-Stroke

Prevention

PROBIOTICS · GUT-HEART AXIS · META-ANALYSIS OF 9 RCTs

Effect of Probiotics on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials.

Khalesi, S., et al. (2014). Hypertension, 64(4), 897–903.

Across 9 randomised trials and 543 adults, probiotics modestly lowered blood pressure. The effect was larger with several strains, daily use for at least 8 weeks, and in people whose blood pressure started higher. Healos™ uses a multi-strain blend for this reason.

RELEVANT TO :

Post-Cardiac

Prevention

Why Healos™, not a bottle off the shelf

A bottle gives you a nutrient. Healos™ gives you a measured result.

CellularUbiquinol CoQ10, NMN and AKG, chosen for how cells make energy and repair.
SystematicThree stages over 91 days, pharmacist-reviewed around your medications.
IntegrativeWorks alongside your care team, never instead of it.
Results you can seeH-Index™ and blood results tracked, backed by our Results Guarantee.
Find my program

Made in cGMP-certified facilities. Certificates of analysis on request.

19 INTERNATIONAL CERTIFICATIONS

Quality that is independently verified.

Not self-declare.

Every Healos™ cellular nutrition product uses endogenous molecules and bio-identical compounds, certified across

19 independent international standards. For a patient taking supplements alongside complex cardiac medications,

these certifications are not marketing — they are the assurance that what is on the label is what is in the capsule,

produced in conditions that pharmaceutical patients deserve.

MANUFACTURING

FDA-Registered Facility

The manufacturing facility is registered with the US Food and Drug Administration — meeting the same facility standards applied to pharmaceutical manufacturing environments.

CLINICAL REFERENCE

PDR Listed

Listed in the Physicians' Desk Reference — the standard clinical reference database consulted by physicians and pharmacists across North America when reviewing supplement interactions.

MANUFACTURING

cGMP Certified

Current Good Manufacturing Practice — the same quality standard applied to licensed pharmaceutical production. Every batch is produced, tested, and documented to pharmaceutical-grade specifications.

CANADIAN FEDERAL LICENSING

NPN

Each Healos™ formulation carries an individual 8-digit Natural Product Number (NPN) — Health Canada's federal pre-market authorization confirming safety, quality, and legal sale in Canada.

INGREDIENT VERIFICATION

Halal Certified

Independent Halal certification verifying ingredient sources, processing methods, and absence of prohibited substances — an additional independent purity verification layer beyond standard supplement testing.

INGREDIENT VERIFICATION

Kosher Certified

Rabbinical kosher certification adds a stringent independent review of ingredient sourcing and processing — widely regarded in the supplement industry as a second rigorous purity verification tier.

INGREDIENT PURITY

USDA Organic

US Department of Agriculture organic certification — confirming that plant-derived ingredients are free from synthetic pesticides, herbicides, and chemical fertilisers across the full supply chain.

INGREDIENT INTEGRITY

Non-GMO Verified

Independent genetic testing confirming that all plant-derived ingredients in the Healos™ formulation are free from genetically modified organisms across the entire supply chain.

THIRD-PARTY TESTING

NSF Certified

National Sanitation Foundation certification — one of the most rigorous independent supplement quality programmes globally, testing for over 270 substances banned in sport and verifying label accuracy.

SPORT & PURITY

Informed Sport Certified

Informed Sport is the global standard for supplements used by professional and Olympic athletes — certifying that every batch is free from substances prohibited by WADA. If it is clean enough for elite sport, it is clean enough for cardiac patients on complex medications.

EUROPEAN COMPLIANCE

SQF / EU Compliant

Safe Quality Food programme certification meeting European Union food safety and quality standards — enabling international distribution and confirming compliance with stringent EU supplement regulations.

ADDITIONAL CERTIFICATES

+6 Further Certifications

The full 19-certification stack includes additional quality, purity, and safety verifications. Complete certification documentation is available on request for institutional partners, pharmacists, and clinical reviewers.

Important compliance note: "FDA-registered facility" refers to the registration status of the manufacturing facility with the US Food and Drug Administration — it does not constitute FDA approval of any Healos™ product as a pharmaceutical drug or medical device. All Healos™ products are dietary supplements, classified as complementary support to medical care. No product makes pharmaceutical drug claims. Certifications apply to the manufacturing facilities and compound quality standards supplying the Healos™ ecosystem and are maintained by the respective manufacturers. Full certification documentation is available to clinical partners on request.

MODALITY COMPARISON

The 360° Comparative Blueprint

of Cardiovascular Recovery Approaches

How four recovery approaches compare across the dimensions that matter most to post-surgical patients.

Data drawn from clinical guidelines, published outcomes research, and standard-of-care documentation.

Competitor descriptions represent general category characteristics based on publicly available information and published clinical guidelines, not any single named provider or product. Individual provider offerings vary. Healos™ products are dietary supplements, not pharmaceutical drugs — they are not intended to diagnose, treat, cure, or prevent any disease, and are designed as complementary support alongside your prescribed medical care, never a replacement for it.

Always consult your physician, cardiologist, or pharmacist before starting any new supplement programme.

THE HEALOS™ CELLULAR NUTRITION STACK

Nutrients that reach where

conventional supplements cannot.

Every compound below is endogenous or bio-identical — molecules the body already recognises

— engineered to survive the digestive journey and reach cellular targets at therapeutic concentrations.

90%+ target absorption rates · Zero synthetic chemical toxicity · 19 international quality certifications.

Molecular Hydrogen (H₂)

The world's smallest antioxidant molecule

At 2 daltons, H₂ is small enough to reach every cellular compartment — including mitochondria and neural tissue — that larger antioxidants cannot access. Selectively neutralises the most damaging reactive oxygen species without disrupting beneficial cellular signalling. Particularly relevant for post-Covid microvasculature inflammation and subclinical vascular oxidative stress.

Cellular reach

~97%

cGMP

PDR-listed

Informed

SOD — Acid/Alkali-Stable

Superoxide Dismutase · Proprietary stable form

Standard SOD supplements are destroyed by stomach acid — less than 10% reaches target tissues. Healos™ uses a proprietary acid/alkali-stable form that survives the digestive environment intact. SOD neutralises superoxide — the free radical most elevated in chronic vascular inflammation and the primary driver of endothelial damage years before a cardiac event.

Target bioavailability

~92%

Proprietary stable form

PDR-listed

cGMP

Ultra-pure NMN

Nicotinamide Mononucleotide · NAD+ precursor

NAD+ is the coenzyme that powers cellular energy production and DNA repair in every cell. It declines 50% between ages 40 and 60 — and is further depleted by stress, chronic disease, and Covid-19 infection. NMN restores NAD+ levels, activating SIRT1 pathways that regulate vascular inflammation and support mitochondrial longevity.

Absorption rate

~95%

cGMP

Summit Purity

Halal

Kosher

CoQ10 (Ubiquinol) + PQQ

Mitochondrial electron carrier + biogenesis activator

CoQ10 as Ubiquinol — the bioavailable reduced form — powers mitochondrial ATP production in cardiac muscle. PQQ promotes mitochondrial biogenesis — the creation of new, functional mitochondria — a capacity suppressed by statins and age. Together they form the Stage B energy restoration core for prevention patients on long-term cardiac medications.

Ubiquinol absorption

~93%

cGMP

Non-GMO

Halal

AKG

Alpha-Ketoglutarate · Krebs cycle intermediate

AKG is a naturally occurring intermediate in the cellular energy cycle supporting detoxification, neurotransmitter balance, and mitochondrial efficiency. In the prevention context, AKG leads Stage A — clearing accumulated oxidative and inflammatory burden before replenishment begins. Also supports healthy epigenetic ageing markers relevant to cardiovascular longevity.

Celular uptake

~88%

Summit Purity

PDR listed

Informed Sport

Alpha - GPC

Nicotinamide Mononucleotide · NAD+ Precursor

Alpha-GPC is a highly bioavailable choline precursor that crosses cellular membranes to support acetylcholine synthesis — the neurotransmitter critical for memory, attention, and cognitive resilience. For prevention patients concerned about cognitive ageing or post-Covid brain fog, Alpha-GPC supports the neural cellular environment that protects against both cognitive decline and cerebrovascular disease.

Target absorption

~90%

FDA-Registered

HALAL

Organic

Absorption figures represent target rates based on compound-specific preclinical and early clinical research. Individual bioavailability varies. All Healos™ products are dietary supplements — complementary support, not pharmaceutical prevention drugs. Always consult your physician before adding supplements, particularly if on prescription medications.

RECOVERY TIMELINE - HONEST EXPECTATION

What happens to your body — and When

Cellular recovery isn't fast, but it is measurable. This timeline reflects recovery after a stent or bypass, and prevention.

After a stroke, recovery is slower and can continue for two to three years; congenital heart disease calls for lifelong care.

STAGE A · SEE RESULTS

Days 1–30

Clearing the oxidative load left by surgery and medication.

Many people notice changes in energy or sleep first. Weekly check-ins keep you on track.

STAGE B+C · CELLULAR RESET

Days 31–91

Restoring cellular energy, then supporting repair. A Day-45 review adjusts your protocol; at Day 91 we analyse your before-and-after blood results.

CONSOLIDATION LOWER RISK

Months 4–12

Deep cellular repair continues. Moderate-severity patients see consistent blood panel normalisation. Recurrence risk environment reducing.

LONG-TERM BASELINE

Month 12+

New cellular baseline established. Program transitions to maintenance mode. People with more complex disease often need longer.

Timeline varies by condition severity, medication regimen, age, and protocol adherence. Individual results may vary. All Healos™ products are complementary support to specialist care — not standalone treatment.

Insights · Blog

Cellular Science,

Made Readable

For post-surgical patients, caregivers, and clinicians who want to go deeper. New articles every two weeks.

NUTRITION SCIENCE

Why your statin is quietly depleting CoQ10 —and what that means for your heart?

Statins block the same pathway that produces CoQ10 — a molecule your mitochondria need to generate energy. Here's the mechanism, the risk, and the evidence-based response.

8 min read · Complementary to specialist care

RECURRENCE RISK

The 30–40% recurrence problem:

what the NEJM and AHA data actually say

One in three cardiac patients experiences a second event within five years. The data points to a single common driver that standard care systematically fails to address.

10 min read · Peer-reviewed sources

MIND - BODY

Fear of recurrence after cardiac surgery:

the invisible burden the system ignores

AHA 2024 research confirms: fear of having another heart attack persists for 6–8 months post-event — independent of anxiety and depression. Here's why that matters for recovery.

7 min read · AHA 2024 data

91-DAY SCIENCE

What actually happens to your vascular cells

in 91 days — a timeline

Vascular endothelial cells turn over on a 90-120 day cycle. The Healos™ 91-day protocol is timed to this biology. Here's what the research says about cellular renewal windows.

9 min read · Cell Metabolism · Das et al. 2018

Not ready yet? Try to check your own cellular data:

Our Healos™ journey can start with a free H-Index™ audit — you receive your score and a summary snapshot at no cost.

WHAT GETS MEASURED

32 dimensions, six systems.

Standard bloodwork and a 20-minute appointment capture a fraction of what's actually

happening in your recovery. The H-Index™ was built to close that gap.

Cardiac & Vascular

7 dimensions

hs-CRP inflammation trend · CoQ10 status · endothelial markers · blood pressure pattern · vascular age indicators

Metabolic & Mitochondrial

6 dimensions

Fasting glucose trend · NAD+ proxy markers · mitochondrial fatigue score · nutrient depletion risk from medications

Sleep & Recovery

5 dimensions

Sleep quality · melatonin suppression

risk (beta-blockers) · recovery consistency · energy pattern across the day

Neurological

5 dimensions

Cognitive clarity · focus & memory self-report · neural inflammation risk markers (stroke-relevant)

Drug - Nutrient Interaction

5 dimensions

Statin-CoQ10 · beta-blocker-melatonin · ACE inhibitor-zinc · diuretic-electrolyte · Warfarin-K2 screening

Mind - Body

4 dimensions

Fear of recurrence · hypervigilance · Mind-Body coefficient (×0.4–1.3) · psychological recovery multiplier

NoHeartAttack.com

Healos™ Canada — Integrative cellular recovery for post-cardiac, post-stroke, and ACHD patients.

Canada.USA.Mexico.Japan.China.Singapore.Australia...

[email protected]

SMS & voicemail: 365.909.2567

Ottawa, Ontario, Canada

© 2026 Healos™ Canada · NoHeartAttack.com · Ottawa, Ontario Privacy - Terms - Refunds

Healos™ programmes are dietary supplements and integrative wellness services. They are not medical advice, not medical treatment, and not a substitute for professional medical care.

Always consult your physician, cardiologist, or pharmacist before starting any new supplement programme. In case of cardiac emergency, call 911 immediately. Healos™ Canada